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In Pursuit of Elegance

A nice article about Dr. Mark Bear from the MIT Spectrum.

The first time his laboratory colleagues broke out the champagne, Mark Bear was barely old enough to drink it. Still an undergraduate, Mark had uncovered a new neural connection in the brain. “I was amazed that there were still tremendous discoveries to be made in this field,” he recalls. “It was a turning point in my decision to pursue basic research.”

Today, it’s hard to say which aspect of Bear’s career is most celebrated, but his work on Fragile X Syndrome, the leading inherited cause of mental retardation, has garnered considerable attention. If Bear’s hypothesis proves true, a neurotransmit- ter receptor called mGluR could reverse Fragile X’s devastating symptoms –– like seizures, memory problems, altered brain development, and abnormal growth.

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Originally posted on Spectrum

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